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[再生障碍性贫血和急性白血病中骨髓细胞增殖活性的研究]

[Study of the proliferative activity of the bone marrow cells in hypoplastic anemia and acute leukemia].

作者信息

Osmanliev P, Kozinets G, Sukiasova T, Shishina R, Faĭnshteĭn F

出版信息

Vutr Boles. 1977;16(1):85-8.

PMID:898917
Abstract

Autoradiographic investigations were carried out on bone marrow cells with thymidine H3 in patients with hypoplastic anemia and acute leukosis in hypoplastic phase. In all patients with hypoplastic anemia a considerable decrease of the labelled cells per cent was observed and in four of the patients in a period of exacerbation, two--in remission--no labelled cells were found. In patients with hypoplastic phase of acute leukosis the proliferative activity was absent. The injury of the bone marrow in case of hypoplastic anemia is supposed to occur at the different stages of hemopoesis.

摘要

对再生障碍性贫血患者以及处于增生低下期的急性白血病患者的骨髓细胞进行了用氚标记胸腺嘧啶核苷的放射自显影研究。在所有再生障碍性贫血患者中,均观察到标记细胞百分比显著下降,并且在4例处于病情加重期的患者中,2例处于缓解期的患者未发现标记细胞。处于急性白血病增生低下期的患者没有增殖活性。再生障碍性贫血时骨髓的损伤被认为发生在造血的不同阶段。

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