核糖体蛋白L11的RNA结合结构域在结构上与同源结构域相似。
The RNA binding domain of ribosomal protein L11 is structurally similar to homeodomains.
作者信息
Xing Y, Guha Thakurta D, Draper D E
出版信息
Nat Struct Biol. 1997 Jan;4(1):24-7. doi: 10.1038/nsb0197-24.
PMID:8989317
Abstract
The RNA binding domain of ribosomal protein L11 is strikingly similar to the homeodomain class of eukaryotic DNA binding proteins: it contains three alpha-helices that superimpose with homeodomain alpha-helices, and some conserved residues required for rRNA recognition align with homeodomain helix III residues contacting DNA bases.
摘要
核糖体蛋白L11的RNA结合结构域与真核生物DNA结合蛋白的同源结构域类别极为相似：它包含三个与同源结构域α螺旋重叠的α螺旋，并且一些rRNA识别所需的保守残基与同源结构域螺旋III中与DNA碱基接触的残基对齐。
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