Campion M J, Greenberg M D, Kazamel T I
Department of Gynecology, Graduate Hospital, Philadelphia, Pennsylvania, USA.
Obstet Gynecol Clin North Am. 1996 Dec;23(4):783-809. doi: 10.1016/s0889-8545(05)70277-1.
Over the past decade, the ever-increasing volume of evidence implicating HPV types in genital neoplasia has stimulated much research interest into all aspects of the biology of this interesting group of viruses. This research has led to the identification of growing heterogeneity of HPV types. It is not surprising, therefore, that the clinical profile of disease associated with genital HPV types is much broader than previously recognized. Knowledge of this clinical spectrum is mandatory to the understanding of the possible role of specific HPV types in human carcinogenesis.
在过去十年中，越来越多的证据表明人乳头瘤病毒（HPV）类型与生殖器肿瘤有关，这激发了人们对这类有趣病毒生物学各个方面的浓厚研究兴趣。这项研究导致了HPV类型异质性的不断发现。因此，与生殖器HPV类型相关疾病的临床特征比以前认识的要广泛得多也就不足为奇了。了解这一临床谱对于理解特定HPV类型在人类致癌过程中的可能作用至关重要。
