Tn5431是由Tn3转座到Tn1721中产生的。

Tn5431 arose by transposition of Tn3 into Tn1721.

作者信息

Zgur-Bertok D, Ambrozic J, Grabnar M

机构信息

Department of Biology, Biotechnical Faculty, University of Ljubljana, Slovenia.

出版信息

Can J Microbiol. 1996 Dec;42(12):1274-6. doi: 10.1139/m96-166.

DOI:10.1139/m96-166

PMID:8989866

Abstract

To further characterize Tn5431, which is composed of Tn3 and Tn1721, DNA sequencing was carried out. It was demonstrated that Tn5431 arose by transposition of Tn3 into Tn1721. Multiple mutations in the Tn3 tnpA gene have occurred, rendering the Tn3 portion of Tn5431 transposition defective and ensuring the simultaneous transposition of the antibiotic resistance determinants on Tn3 and Tn1721.

摘要

为了进一步表征由Tn3和Tn1721组成的Tn5431，进行了DNA测序。结果表明，Tn5431是由Tn3转座到Tn1721中产生的。Tn3的tnpA基因发生了多个突变，使Tn5431的Tn3部分转座有缺陷，并确保了Tn3和Tn1721上抗生素抗性决定簇的同时转座。