Adetunji O F, Akinshipe B O, Ogunbodede E O, Ijaware C O
Department of Medical Microbiology and Parasitology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Cent Afr J Med. 1996 Aug;42(8):249-52.
To determine the relationship between bacterial colonization of tooth surfaces and dental caries, selective agar media-MM10 Sucrose, Rogosa SL and Blood agar were used to isolate bacteria from the scrappings of 60 tooth surfaces of 30 children and young adults. Mean age +/- SD was 13.3 +/- 4.1 (range seven to 19 years). Streptococcus mutans was isolated from 36 surfaces representing 60pc Lactobacillus species from 38 surfaces (68pc), and Actinomyces species from 12 surfaces (20pc). The individual prevalences of these organisms decreased with age. The distribution of bacteria according to surfaces examined showed that the pits and fissures were the main habitat of Streptococcus mutans and Lactobacilli were sensitive to erythromycin. Actinomyces species were 100pc sensitive to Penicillin. All the bacteria species isolated were also found to be 100pc sensitive to Olfoxacin (Tarivid). It is suggested that the use of antibiotics may stop the growth of cariogenic bacteria in individuals and thereby contribute to a decline in the incidence and prevalence of dental caries in the community.
为了确定牙面细菌定植与龋齿之间的关系，使用选择性琼脂培养基——MM10蔗糖培养基、罗氏乳杆菌培养基和血琼脂培养基，从30名儿童和青年的60个牙面刮屑中分离细菌。平均年龄±标准差为13.3±4.1岁（范围为7至19岁）。从36个牙面分离出变形链球菌，占60%；从38个牙面（68%）分离出乳杆菌属；从12个牙面（20%）分离出放线菌属。这些微生物的个体患病率随年龄下降。根据检查的牙面分布情况，窝沟是变形链球菌的主要栖息地，且乳杆菌对红霉素敏感。放线菌属对青霉素100%敏感。所有分离出的细菌种类对氧氟沙星（泰利必妥）也100%敏感。有人提出，使用抗生素可能会阻止个体中致龋菌的生长，从而有助于降低社区中龋齿的发病率和患病率。
