Chow S N, Chen C D, Chen Y P, Hsieh C Y
Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
J Formos Med Assoc. 1996 Nov;95(11):851-6.
A 16-year review of borderline tumors of the ovary was carried out to study the clinical features and outcomes of patients and to assess the value of color Doppler ultrasound in preoperative diagnosis. The records of 53 patients with borderline tumors of the ovary were retrospectively analyzed for clinical features, sonographic findings and survival. Twenty-three of 44 patients with stage I disease were treated conservatively without recurrence. Seven of eight (87.5%) patients with stage III disease developed recurrent or persistent tumors within 3 years. Overall, eight of 53 (15.1%) patients had recurrent or persistent disease. Twenty-three of 44 (52.3%) patients with borderline ovarian tumors showed morphologic malignancy by gray-scale sonography. Ten of 13 (76.9%) patients who had color Doppler ultrasound examination had detectable intratumoral blood flow. The mean resistance index value was 0.47 (range, 0.3-0.6). Three of these patients (30%) had a resistance index value < 0.4. The results indicated that the extent of disease as reflected by the clinical stage was the main factor for prediction of recurrence, and borderline tumors of the ovary were not efficiently differentiated from benign or malignant tumors by resistance index values obtained from color Doppler ultrasound.
对卵巢交界性肿瘤进行了一项为期16年的回顾性研究，以探讨患者的临床特征和预后，并评估彩色多普勒超声在术前诊断中的价值。对53例卵巢交界性肿瘤患者的临床特征、超声检查结果及生存情况进行回顾性分析。44例I期患者中有23例接受保守治疗，无复发。8例III期患者中有7例（87.5%）在3年内出现复发或持续性肿瘤。总体而言，53例患者中有8例（15.1%）出现复发或持续性疾病。44例卵巢交界性肿瘤患者中有23例（52.3%）在灰阶超声检查中表现出形态学上的恶性特征。13例接受彩色多普勒超声检查的患者中有10例（76.9%）可检测到肿瘤内血流信号。平均阻力指数值为0.47（范围0.3 - 0.6）。其中3例患者（30%）阻力指数值<0.4。结果表明，临床分期所反映的疾病范围是预测复发的主要因素，彩色多普勒超声所获得的阻力指数值无法有效区分卵巢交界性肿瘤与良性或恶性肿瘤。
