Tsai M H, Pai H H, Yen P T, Huang T S, Ho Y S
Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC.
J Formos Med Assoc. 1996 Nov;95(11):877-80.
A 19-year-old male was admitted to our clinic because of nasal obstruction and intermittent postnasal drip of 3 to 4 years' duration. Physical examination revealed a wide-based, smooth-surfaced nasopharyngeal tumor which was suspected to be a nasopharyngeal angiofibroma after examination of computed tomographic scans and an angiogram. However, after the tumor was removed by surgical excision via a transpalatal approach, the pathologic examination revealed Castleman's disease of the hyaline-vascular type. There was neither evidence of recurrence nor nasal problems at 4 years' follow-up. To our knowledge, Castleman's disease, or angiofollicular lymph node hyperplasia, may present as a local or generalized tumor-like condition, usually in the chest or abdomen, and may involve both the lymph nodes and non-nodal tissues. A review of previous articles reveals that there has not been any report of Castleman's disease found in the nasopharynx. This rare disorder is presented and discussed.
一名19岁男性因鼻塞和持续3至4年的间歇性鼻后滴漏症状入住我院。体格检查发现一个基底较宽、表面光滑的鼻咽部肿瘤，经计算机断层扫描和血管造影检查后怀疑为鼻咽血管纤维瘤。然而，经经腭入路手术切除肿瘤后，病理检查显示为透明血管型Castleman病。随访4年，既无复发迹象，也无鼻腔问题。据我们所知，Castleman病，即血管滤泡性淋巴结增生，可能表现为局部或全身性肿瘤样病变，通常发生在胸部或腹部，可能累及淋巴结和非淋巴结组织。回顾以往文献发现，尚未有在鼻咽部发现Castleman病的报道。现介绍并讨论这种罕见疾病。
