Nauciel C, Guilhin P, Matsiota-Bernard P, Ronco E
Service de Microbiologie, Hôpital Raymond Poincaré, Garches.
Presse Med. 1996 Nov 23;25(36):1786-8.
Evaluate etiological circumstances and prognosis in Legionnaires' disease.
A series of 81 culture-proven cases of Legionnaires' disease was collected in the Paris area between 1989 and 1994.
Direct immunofluorescence assay was positive for Legionella pneumophilia in 48% of the cases. Serogroup 1 was isolated in 88% of the cases. The median age of the patients was 51 years and 74% were males. Infection was nosocomial in 28% of the cases. Immunosuppression was present in 45% of the patients (transplantation, cancer, leukemia). Among the immunosuppressed patients, 7 were HIV-infected. Mortality due to legionellosis reached 27%. This high mortality was probably related to patient selection criteria.
Mortality from Legionnaires' disease remains high as confirmed in this series.
评估军团病的病因及预后。
1989年至1994年间在巴黎地区收集了一系列81例经培养证实的军团病病例。
48%的病例中嗜肺军团菌直接免疫荧光检测呈阳性。88%的病例分离出1血清型。患者的中位年龄为51岁，74%为男性。28%的病例感染为医院获得性。45%的患者存在免疫抑制（移植、癌症、白血病）。在免疫抑制患者中，7例感染了HIV。军团菌病导致的死亡率达27%。这种高死亡率可能与患者选择标准有关。
本系列研究证实，军团病的死亡率仍然很高。
