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[亚急性脊髓视神经病患者的死亡率与其残疾状况的关系]

[Mortality of SMON patients in relation to their disabilities].

作者信息

Kuroda K, Tatara K, Lee B, Suzuki T, Morisada K

机构信息

College of Social Welfare, Osaka Prefecture University.

出版信息

Nihon Koshu Eisei Zasshi. 1996 Mar;43(3):231-7.

PMID:8991499
Abstract

The relationship between mortality and disability, was studied in SMON patients, who had participated in the questionnaire survey in 1980, by following them for 10 years through municipal resident registration information offices. Eighty deaths were observed among 409 subjects during the follow-up period. The effect of each disability on the mortality of SMON was estimated by applying the Cox proportional hazard model. The presence of severe gait disturbance and low levels of activities of daily living (ADL) were associated with significantly higher risk of death after adjustment for age and sex. The relative risk of visual disturbance was not significant after adjusting for age, sex and other kinds of disability. Those who complained of continuous dysesthesia at the time of the initial survey showed better prognosis than those without such dysesthesia. Among subjects who died during the follow-up period, those who had reported low levels of ADL at the time of the initial survey had a greater proportion of deaths attributable to heart failure and pneumonia than those who had reported high levels of ADL.

摘要

通过市居民登记信息办公室对1980年参与问卷调查的亚急性脊髓视神经病(SMON)患者进行为期10年的随访,研究了死亡率与残疾之间的关系。在随访期间,409名受试者中有80人死亡。应用Cox比例风险模型估计了每种残疾对SMON死亡率的影响。在对年龄和性别进行调整后,严重步态障碍和低水平日常生活活动(ADL)与显著更高的死亡风险相关。在对年龄、性别和其他类型残疾进行调整后,视觉障碍的相对风险不显著。在初次调查时主诉持续感觉异常的患者比没有这种感觉异常的患者预后更好。在随访期间死亡的受试者中,初次调查时报告ADL水平低的患者因心力衰竭和肺炎导致的死亡比例高于报告ADL水平高的患者。

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