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[An EPR study of the joint action of sodium nitrite and whole-body irradiation on animal tissues].

作者信息

Kudriavtsev M E, Dmitrieva O N, Kuropteva Z V

出版信息

Izv Akad Nauk Ser Biol. 1996 Jul-Aug(4):453-9.

PMID:8991528
Abstract

Changes in metabolic paramagnetic centers of the liver, kidney, spleen, brain and heart tissues, and blood after sodium nitrite intraperitoneal administration irradiation, or combined action of sodium nitrite and irradiation on mice, were studied using the EPR method. It was shown that irradiation of mice after sodium nitrite administration enhanced the effects induced by sodium nitrite alone: the levels of nitrosyl complexes Heme-NO in the tissues, cytochrome P-450 inhibition, and MetHb were higher.

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