Kurganova I I, Klimchuk N D
Mikrobiol Z. 1996 Jul-Aug;58(4):80-5.
It was shown in the experiments on the model of typhus infection in guinea-pigs that the pathogenic organism can be inherited by foetus from the mother's organism in the period of acute infection. It is confirmed by the presence of positive seroconversion in 86% of born offsprings and the character of the immunity response after the control infection that is the initial formation of immunoglobulins of form G (Ig G). At the same time there was no such a transfer of pathogenic organisms in 14% of offsprings. This fact is testified by the absence of seroconversion and the initial formation of immunoglobulins of form M (Ig M) with following formation of immunoglobulins of form G (Ig G) after control infection rickettsia Prowazekii.
在豚鼠斑疹伤寒感染模型实验中表明,致病生物体可在急性感染期由母体传给胎儿。86%的新生后代出现阳性血清转化以及对照感染后免疫反应的特征(即G型免疫球蛋白(Ig G)的初步形成)证实了这一点。同时,14%的后代没有发生致病生物体的这种传播。普氏立克次体对照感染后没有血清转化以及M型免疫球蛋白(Ig M)的初步形成随后才形成G型免疫球蛋白(Ig G)这一事实证明了这一点。