[子宫平滑肌肉瘤：一种令人惊讶的病理学。文献综述。六例病例报告]
[Uterine leiomyosarcomas: a surprising pathology. Review of the literature. Six case reports].
作者信息
Durand-Réville M, Dufour P, Vinatier D, Martin de Lassalle E, Lucot J P, Monnier J C, Lecomte-Houcke M, Puech F
机构信息
Service de Gynécologie-Obstétrique, Hôpital Jeanne-de-Flandre, Lille.
出版信息
J Gynecol Obstet Biol Reprod (Paris). 1996;25(7):710-5.
OBJECTIVE
The aim of this study was to determine the clinical features and laboratory tests which define a population with a high risk of leiomyosarcoma.
METHOD
A retrospective analysis of 660 hysterectomies performed between 1989 and 1994 was conducted. There were 414 cases of leiomyoma and 6 leiomyosarcomas (1.4%).
RESULTS
The indication for hysterectomy was complication of fibromyomatous uterus in all cases. Diagnosis of leiomyosarcoma was never suspected before surgery and the pathology examination. Complimentary radiotherapy was given in 2 patients among the 6 with leiomyosarcoma. Mean survival was 35 months. There were no cases of recurrence or metastasis. None of the laboratory tests performed provided clues to diagnosis.
CONCLUSION
Physicians should be aware of possible misdiagnosis of a leiomyosarcoma when proposing medical treatment of uterine fibroma.
目的
本研究旨在确定界定平滑肌肉瘤高风险人群的临床特征和实验室检查。
方法
对1989年至1994年间进行的660例子宫切除术进行回顾性分析。其中有414例平滑肌瘤和6例平滑肌肉瘤（1.4%）。
结果
所有病例子宫切除术的指征均为纤维瘤性子宫并发症。术前及病理检查均未怀疑平滑肌肉瘤的诊断。6例平滑肌肉瘤患者中有2例接受了辅助放疗。平均生存期为35个月。无复发或转移病例。所进行的实验室检查均未提供诊断线索。
结论
在对子宫纤维瘤进行药物治疗时，医生应意识到平滑肌肉瘤可能被误诊。
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