Stoianov Kh, Vŭlchev D, Karashmalŭkov A, Iuliianov A
Khirurgiia (Sofiia). 1996;49(2):17-20.
A total of 232 patients with obturation ileus, caused by locally advanced colorectal carcinoma, are operated over a 12-year period (1979-1990). In 160 patients (68.97 per cent) the tumor is located in the colon, and in 72 (31.03 per cent)-in the rectum. The operative interventions performed are distributed as follows: 122 (52.58 per cent) radical, and 110 (47.42 per cent) palliative. There are 84 patients (36.03 per cent) in IV clinical stage. Postoperative lethality among those subjected to radical operation amounts to 25.41 per cent, with leading underlying causes-peritonitis (35.08 per cent) and serious ileus intoxication (21.05 per cent). The survival over 1, 3 and 5-year periods among those radically operated is 74.59, 48.37 and 34.06 per cent, respectively. Histologically differentiated adenocarcinoma is demonstrated in 69.38 per cent, undifferentiated-in 17.50 per cent, and mucinous adenocarcinoma-in 13.12 per cent. The factors with a high prognostic value include: stage of primary tumor development, lymph involvement, type of operative intervention and histological variant of the neoplasm.
在12年期间(1979 - 1990年),对总共232例因局部晚期结直肠癌导致肠梗阻的患者进行了手术。其中160例(68.97%)肿瘤位于结肠,72例(31.03%)位于直肠。所进行的手术干预分布如下:根治性手术122例(52.58%),姑息性手术110例(47.42%)。处于临床IV期的患者有84例(36.03%)。接受根治性手术患者的术后死亡率为25.41%,主要潜在原因是腹膜炎(35.08%)和严重肠梗阻中毒(21.05%)。接受根治性手术患者1年、3年和5年的生存率分别为74.59%、48.37%和34.06%。组织学上,分化型腺癌占69.38%,未分化型占17.50%,黏液腺癌占13.12%。具有高预后价值的因素包括:原发肿瘤发展阶段、淋巴结受累情况、手术干预类型和肿瘤的组织学类型。