[膜增生性肾小球肾炎中慢性肾衰竭的预测因素]
[Factors predicting chronic renal failure in membranoproliferative glomerulonephritis].
作者信息
Dobronravov V A
机构信息
Department of Internal Diseases Propaedeutics, State University of IP Pavlov, Saint-Petersburg.
出版信息
Klin Med (Mosk). 1996;74(7):29-33.
Multivariate analysis of overall clinicomorphological signs in 58 patients with membranoproliferative glomerulonphiritis (MPG) and investigation of functional survival outlined independent prognostic factors valuable for predicting progression of chronic renal failure. These were: exacerbation > 1 time in 3 years, secondary hypertension, concentration of serum creatinine > 0.13 mmol/l, marked tubulointerstitial changes, global glomerular sclerosis > 30%, 24-hour proteinuria > 8 g.
对58例膜增生性肾小球肾炎（MPG）患者的总体临床形态学体征进行多变量分析，并对功能存活情况进行研究，确定了对预测慢性肾衰竭进展有价值的独立预后因素。这些因素包括：3年内病情加重>1次、继发性高血压、血清肌酐浓度>0.13 mmol/l、明显的肾小管间质改变、全球肾小球硬化>30%、24小时蛋白尿>8 g。
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