Barbato A, Roviello F, De Stefano A, Marrelli D, Messano A, Guarnieri A, Pinto E
Istituto Policattedra di Scienze Chirurgiche, Università degli Studi, Siena.
Minerva Chir. 1996 Jun;51(6):475-9.
The authors describe a case of somatostatinoma localized in the body and tail of the pancreas. They emphasize the rarity of this finding (only 33 cases with certain pancreatic localization are reported in literature) and the absence of a distinctive syndrome, which could direct to an early diagnosis, the authors are in doubt about the real incidence of this disease. The absence, generally, of a distinctive syndrome, the poor condition of these patient and then the lack of surgical treatment and histological examination, could lead to a lower valuation. Delayed diagnosis and then the local extension of this neoplasm often make surgical treatment vain. Nevertheless since somatostatinoma has more possibilities of radical resection than pancreatic cancer, it's required to know its features and course so to increase possibilities of an early diagnosis. In fact disregarding surgical treatment, the survival of these patients, one year after diagnosis, is about 48%. This result is better than the survival of patients with pancreatic or biliary duct cancers. Current diagnostic procedures are reported.
作者描述了一例位于胰腺体尾部的生长抑素瘤病例。他们强调了这一发现的罕见性（文献中仅报道了33例明确位于胰腺的病例）以及缺乏可指导早期诊断的独特综合征，作者对这种疾病的实际发病率表示怀疑。一般来说，由于缺乏独特综合征、这些患者状况较差，进而缺乏手术治疗和组织学检查，可能导致对其评估较低。诊断延迟以及随后该肿瘤的局部扩展常常使手术治疗徒劳无功。然而，由于生长抑素瘤比胰腺癌有更多的根治性切除可能性，因此需要了解其特征和病程，以便增加早期诊断的可能性。事实上，不考虑手术治疗，这些患者在诊断后一年的生存率约为48%。这一结果优于胰腺癌或胆管癌患者的生存率。文中还报道了当前的诊断程序。
