[The endogenous intoxication syndrome and the procedure for detoxication therapy in the treatment of suppurative diseases of the face and neck].

A total of 470 patients with inflammatory diseases of the maxillofacial area and neck were examined and treated. Acute inflammatory process was complicated with sepsis in 87 of them. Clinical and laboratory studies revealed that the intensity of endogenous intoxication depended on the phase of inflammatory process. This helped accurately differentiate between the intoxication degrees and develop detoxication strategy for each of them. Such a differentiated approach helped appreciably decrease the mortality in the group of patients with odontogenic and stomatogenic sepsis.