Popov M E, Kashparov I V, Popov E M
Bioorg Khim. 1996 Jul;22(7):510-22.
Theoretical conformational analysis of a hexapeptide fragment p17-p24 of the native substrate of the HIV-1 protease was reported. The geometrical and energy parameters of all possible optimal conformations were determined. The data which are necessary for the calculation of the mechanism of the catalytic act of HIV-1 protease were obtained.
报道了对HIV-1蛋白酶天然底物六肽片段p17 - p24的理论构象分析。确定了所有可能的最优构象的几何和能量参数。获得了计算HIV-1蛋白酶催化作用机制所需的数据。