Lim L C
Department of Psychological Medicine National University Hospital, Singapore.
Singapore Med J. 1996 Aug;37(4):448-50.
A case of mania following closed head injury to the left hemisphere is reported. The patient presented with a self-limiting manic episode that recovered without treatment. It is postulated that the head injury is the causative factor in this case. This was supported by laboratory results as well as psychological investigations. It is believed that non-dominant right hemisphere injury is related to the development of mania. However, a search of the literature revealed five other cases of mania following left hemispheric injury. Although the mechanisms implicated in the pathogenesis of secondary mania have not been established, this case adds to the growing evidence that head injury may be directly causative in affective psychoses. Therefore, it is premature to conclude that mania is a pathology of the non-dominant right hemisphere.
报告了一例左半球闭合性头部损伤后出现躁狂症的病例。患者表现为自限性躁狂发作，未经治疗即康复。据推测，该病例中头部损伤是致病因素。实验室结果以及心理调查均支持这一点。据信，非优势右半球损伤与躁狂症的发生有关。然而，文献检索发现另外还有5例左半球损伤后出现躁狂症的病例。尽管继发性躁狂症发病机制中涉及的机制尚未明确，但该病例进一步证明了头部损伤可能是情感性精神病的直接病因，这一证据越来越多。因此，现在就得出躁狂症是非优势右半球的一种病变这一结论还为时过早。
