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Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neurotrophic factor for cultured rat cortical neurons.

作者信息

Morio H, Tatsuno I, Tanaka T, Uchida D, Hirai A, Tamura Y, Saito Y

机构信息

Second Department of Internal Medicine, Chiba University School of Medicine, Japan.

出版信息

Ann N Y Acad Sci. 1996 Dec 26;805:476-81. doi: 10.1111/j.1749-6632.1996.tb17507.x.

DOI:10.1111/j.1749-6632.1996.tb17507.x
PMID:8993427
Abstract
摘要

相似文献

1
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neurotrophic factor for cultured rat cortical neurons.垂体腺苷酸环化酶激活多肽(PACAP)是培养的大鼠皮层神经元的一种神经营养因子。
Ann N Y Acad Sci. 1996 Dec 26;805:476-81. doi: 10.1111/j.1749-6632.1996.tb17507.x.
2
Pituitary adenylate cyclase-activating polypeptide protects rat-cultured cortical neurons from glutamate-induced cytotoxicity.
Brain Res. 1996 Nov 25;741(1-2):82-8. doi: 10.1016/s0006-8993(96)00920-1.
3
Neuroprotective action of endogenous PACAP in cultured rat cortical neurons.内源性垂体腺苷酸环化酶激活肽在培养的大鼠皮质神经元中的神经保护作用。
Regul Pept. 2005 Mar 15;126(1-2):123-8. doi: 10.1016/j.regpep.2004.08.014.
4
Neurotrophic and neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on mesencephalic dopaminergic neurons.垂体腺苷酸环化酶激活多肽(PACAP)对中脑多巴胺能神经元的神经营养和神经保护作用。
J Neurosci Res. 1998 Dec 1;54(5):698-706. doi: 10.1002/(SICI)1097-4547(19981201)54:5<698::AID-JNR15>3.0.CO;2-5.
5
Neurotrophic activity of pituitary adenylate cyclase-activating polypeptide on rat cerebellar cortex during development.垂体腺苷酸环化酶激活多肽在大鼠小脑皮质发育过程中的神经营养活性。
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9415-20. doi: 10.1073/pnas.96.16.9415.
6
BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons.脑源性神经营养因子介导垂体腺苷酸环化酶激活肽-38对大鼠皮层神经元的神经保护作用。
Neuroreport. 2001 Apr 17;12(5):919-23. doi: 10.1097/00001756-200104170-00011.
7
Reduction of lipopolysaccharide-induced neurotoxicity in mixed cortical neuron/glia cultures by femtomolar concentrations of pituitary adenylate cyclase-activating polypeptide.飞摩尔浓度的垂体腺苷酸环化酶激活多肽可降低脂多糖诱导的混合皮质神经元/神经胶质细胞培养物中的神经毒性。
Neuroscience. 1999;91(2):493-500. doi: 10.1016/s0306-4522(98)00606-x.
8
Glutamate toxicity in the lung and neuronal cells: prevention or attenuation by VIP and PACAP.
Ann N Y Acad Sci. 1998 Dec 11;865:226-37. doi: 10.1111/j.1749-6632.1998.tb11182.x.
9
The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32.垂体腺苷酸环化酶激活多肽对小脑颗粒细胞的神经保护作用是通过抑制与CED3相关的半胱氨酸蛋白酶caspase-3/CPP32介导的。
Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13390-5. doi: 10.1073/pnas.97.24.13390.
10
[Pituitary adenylate cyclase activating polypeptide ameliorates the damage and inhibits the increase of intracellular calcium concentration in cultured hippocampal neurons induced by glutamate].[垂体腺苷酸环化酶激活多肽改善谷氨酸诱导的培养海马神经元损伤并抑制细胞内钙浓度升高]
Sheng Li Xue Bao. 2000 Oct;52(5):402-6.

引用本文的文献

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Protective Effects of PACAP in Diabetic Complications: Retinopathy, Nephropathy and Neuropathy.垂体腺苷酸环化酶激活肽在糖尿病并发症(视网膜病变、肾病和神经病变)中的保护作用。
Int J Mol Sci. 2025 Oct 3;26(19):9650. doi: 10.3390/ijms26199650.
2
Effects of Pituitary Adenylate Cyclase Activating Polypeptide on Cell Death.垂体腺苷酸环化酶激活肽对细胞死亡的影响。
Int J Mol Sci. 2022 Apr 29;23(9):4953. doi: 10.3390/ijms23094953.
3
Maxadilan prevents apoptosis in iPS cells and shows no effects on the pluripotent state or karyotype.Maxadilan 可防止 iPS 细胞凋亡,并且对多能状态或核型没有影响。
PLoS One. 2012;7(3):e33953. doi: 10.1371/journal.pone.0033953. Epub 2012 Mar 23.
4
PACAP protects against TNFα-induced cell death in olfactory epithelium and olfactory placodal cell lines.PACAP 可防止 TNFα 诱导的嗅上皮和嗅基板细胞系细胞死亡。
Mol Cell Neurosci. 2010 Dec;45(4):345-54. doi: 10.1016/j.mcn.2010.07.007. Epub 2010 Jul 21.
5
Signaling cascades involved in neuroprotection by subpicomolar pituitary adenylate cyclase-activating polypeptide 38.亚皮摩尔垂体腺苷酸环化酶激活多肽38介导神经保护作用的信号级联反应。
J Mol Neurosci. 2005;27(1):91-105. doi: 10.1385/JMN:27:1:091.