PACAP 1-27 and 1-38 in the porcine pancreas: occurrence, localization, and effects.
作者信息
Tornøe K, Hannibal J, Giezemann M, Schmidt P, Holst J J
机构信息
Department of Medical Physiology, Panum Institute, University of Copenhagen, Denmark.
出版信息
Ann N Y Acad Sci. 1996 Dec 26;805:521-35. doi: 10.1111/j.1749-6632.1996.tb17514.x.
Abstract
摘要
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PACAP 1-27 and 1-38 in the porcine pancreas: occurrence, localization, and effects.猪胰腺中的垂体腺苷酸环化酶激活肽1-27和1-38：存在、定位及作用
Ann N Y Acad Sci. 1996 Dec 26;805:521-35. doi: 10.1111/j.1749-6632.1996.tb17514.x.
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Current status of PACAP as a regulator of insulin secretion in pancreatic islets.垂体腺苷酸环化酶激活肽作为胰岛胰岛素分泌调节因子的研究现状
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Effect of stimulators such as GLP-1, PACAP, and nicotinamide on glucose-stimulated insulin secretion from porcine pancreatic endocrine cells in long-term culture.长期培养中，胰高血糖素样肽-1、垂体腺苷酸环化酶激活肽和烟酰胺等刺激物对猪胰腺内分泌细胞葡萄糖刺激的胰岛素分泌的影响。
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Effects of PACAP(1-27) on the canine endocrine pancreas in vivo: interaction with cholinergic mechanism.垂体腺苷酸环化酶激活肽（1-27）对犬体内内分泌胰腺的影响：与胆碱能机制的相互作用
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PACAP as low as 10(-13) M raises cytosolic Ca2+ activity in pancreatic B-cells by augmenting Ca2+ influx through L-type Ca2+ channels to trigger insulin release.低至10^(-13) M的垂体腺苷酸环化酶激活肽（PACAP）通过增加经L型钙通道的钙内流来提高胰腺β细胞的胞质钙活性，从而触发胰岛素释放。
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PACAP is an islet neuropeptide which contributes to glucose-stimulated insulin secretion.垂体腺苷酸环化酶激活肽是一种胰岛神经肽，有助于葡萄糖刺激的胰岛素分泌。
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Effect of PACAP, VIP, glucagon, and GLP1 on cAMP production and insulin release of HIT-T15 cells is passage dependent.垂体腺苷酸环化酶激活肽、血管活性肠肽、胰高血糖素和胰高血糖素样肽-1对HIT-T15细胞环磷酸腺苷生成及胰岛素释放的影响具有传代依赖性。
Ann N Y Acad Sci. 1996 Dec 26;805:634-9. doi: 10.1111/j.1749-6632.1996.tb17533.x.
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