Szalay J, Poteczin E
Zentralbl Gynakol. 1977;99(11):669-73.
The total urinary estrogen values of women with glucosuria were studied by 5 different methods in 287 samples. The spectrophotometry values obtained by Ittrich's reaction have been influenced by urinary glucose concentrations. An increased glucose content appeared to be connected with a decrease of the hormone values if the hydrolysis of conjugates was performed by mineral acids. The most effective method was enzymatic hydrolysis used also for the determination of the acid labile fractions. The determination of total estrogen excretion is necessary for evaluating intrauterine fetal well-being in diabetic mothers.
采用5种不同方法对287份样本中患有糖尿的女性的尿雌激素总量进行了研究。通过伊特里希反应获得的分光光度法值受尿葡萄糖浓度的影响。如果用无机酸进行结合物的水解，葡萄糖含量增加似乎与激素值降低有关。最有效的方法是酶水解，该方法也用于测定酸不稳定部分。测定总雌激素排泄量对于评估糖尿病母亲的宫内胎儿健康状况是必要的。
