Hofmann K D, Wagner F, Preibsch W, Niedner W, Dziambor H, Müller H J
Zentralbl Gynakol. 1977;99(11):674-8.
The behaviour of the beta-glucuronidase activity during the life phases and the phase of the cycle of a woman has been studied in 51 human ovaries after the Dohrmann method. The study clearly indicates a dependency on age, that is demonstrated by a rise in beta-glucuronidase activity from 536 microgram Ph/h/g ovarial tissue during full functioning to 705 microgram Ph/h/g ovarial tissue in the premenopause and by dropping to 529 microgram Ph/h/g ovarial tissue in the menopause and the senium. The premenopause values are significantly higher compared to that of the other two functional phases. The activity of the beta-glucuronidase is significantly higher in the secretory phase than in the proliferation phase. Existing relations between the beta-glucuronidase of the ovary and the gonadotropic hormones of the hypophysis and the oestrogen metabolism are discussed.
采用多尔曼法，对51个女性卵巢在其生命阶段和月经周期各阶段的β-葡萄糖醛酸酶活性进行了研究。该研究清楚地表明了其与年龄的相关性，具体表现为β-葡萄糖醛酸酶活性从功能全盛期的536微克酚/小时/克卵巢组织，上升至绝经前期的705微克酚/小时/克卵巢组织，而在绝经和老年期则降至529微克酚/小时/克卵巢组织。绝经前期的值与其他两个功能阶段相比显著更高。β-葡萄糖醛酸酶的活性在分泌期明显高于增殖期。文中还讨论了卵巢的β-葡萄糖醛酸酶与垂体促性腺激素及雌激素代谢之间的现有关系。
