[Beta-glucuronidase activity in human ovarian tissue during the life- and cycle-phases of the woman].

The behaviour of the beta-glucuronidase activity during the life phases and the phase of the cycle of a woman has been studied in 51 human ovaries after the Dohrmann method. The study clearly indicates a dependency on age, that is demonstrated by a rise in beta-glucuronidase activity from 536 microgram Ph/h/g ovarial tissue during full functioning to 705 microgram Ph/h/g ovarial tissue in the premenopause and by dropping to 529 microgram Ph/h/g ovarial tissue in the menopause and the senium. The premenopause values are significantly higher compared to that of the other two functional phases. The activity of the beta-glucuronidase is significantly higher in the secretory phase than in the proliferation phase. Existing relations between the beta-glucuronidase of the ovary and the gonadotropic hormones of the hypophysis and the oestrogen metabolism are discussed.