Praskov D, Todorov S L, Kavaklova L, Tsilka E, Daneva M
Zentralbl Bakteriol Orig A. 1977 May;238(1):9-15.
The incorporation of labelled precursors of DNA, RNA and proteins in F. cells infected with Coxsackie B4 virus has been traced both in the presence and absence of total histone from nucleated erythrocytes during the infectious process. In comparison with the virus infection alone, the exogenous histone supressed the incorporation of 3H-thymidine in early hours and the incorporation of 3H-uridine and 14C-leucine in the 9th hour after virus infection. The established repression of the incorporation of the labelled precurssors for RNA and proteins correlates with a drop in the order of 90 to 99% in the yield of infectious virus.
在感染过程中，研究了在有和没有来自有核红细胞的总组蛋白存在的情况下，感染柯萨奇B4病毒的F细胞中DNA、RNA和蛋白质标记前体的掺入情况。与单独的病毒感染相比，外源性组蛋白在早期抑制了3H-胸腺嘧啶核苷的掺入，并在病毒感染后第9小时抑制了3H-尿苷和14C-亮氨酸的掺入。已确定的RNA和蛋白质标记前体掺入的抑制与感染性病毒产量下降90%至99%相关。
