Manginas A, Pavlides G, Voudris V, Vassilikos V, Cokkinos D V
Onassis Cardiac Surgery Center, Cardiology Department, Kallithea, Athens, Greece.
Cathet Cardiovasc Diagn. 1997 Jan;40(1):85-91. doi: 10.1002/(sici)1097-0304(199701)40:1<85::aid-ccd17>3.0.co;2-t.
The coronary flow velocity changes in the great cardiac and middle cardiac veins, induced by intracoronary administration of nitroglycerine, adenosine, and during percutaneous transluminal coronary angioplasty, were evaluated in 12 patients with significant coronary stenoses, using the Doppler wire (Flowire). Optimal spectral signals of the time-averaged peak flow velocity were obtained in 10 patients. Nitroglycerine produced no significant flow velocity changes (P = 0.13). Adenosine caused a significant augmentation of flow velocity compared to baseline (P = 0.003). During balloon inflation, venous flow velocity decreased (P = 0.007); however, the venous outflow did not cease. A pronounced venous hyperemic response, following balloon deflation, was also documented. The utility of continuous vein flow velocity monitoring with the Flowire, during high-risk and complicated coronary interventions remains to be elucidated.
在12例有严重冠状动脉狭窄的患者中，使用多普勒导丝（Flowire）评估了冠状动脉内注射硝酸甘油、腺苷以及经皮腔内冠状动脉成形术期间大心静脉和心中静脉的冠状动脉血流速度变化。10例患者获得了时间平均峰值流速的最佳频谱信号。硝酸甘油未引起显著的流速变化（P = 0.13）。与基线相比，腺苷导致流速显著增加（P = 0.003）。球囊扩张期间，静脉流速降低（P = 0.007）；然而，静脉流出并未停止。球囊放气后也记录到明显的静脉充血反应。在高危和复杂冠状动脉介入治疗期间，使用Flowire连续监测静脉流速的效用仍有待阐明。
