Kim H S, Suh J S, Han C D, Kim Y H, Lee J D
Department of Diagnostic Radiology, Medical College of Yonsei University, Seoul, South Korea.
Clin Nucl Med. 1997 Jan;22(1):6-12. doi: 10.1097/00003072-199701000-00002.
To evaluate the distribution and degree of radioactivity on sequential Tc-99m methylene diphosphonate (Tc-99m MDP) scans in the diagnosis of postoperative loosening in asymptomatic patients who underwent cementless total hip replacement.
Tc-99m MDP scans were obtained every three months where possible, for one year in those patients who underwent total hip replacement using a Harris Galante cementless prosthesis. Eighty-three scans from 45 patients were obtained. Uptake was assessed within the five periprosthetic zones (zone 1: greater trochanter; 2: lateral stem of the prosthesis; 3: tip of the prosthesis; 4: medial stem of the prosthesis; and 5: lesser trochanter) using an arbitrary 5-point grading system. Grade 1 indicated normal uptake and Grade 5 indicated highest uptake. The grade of uptake within each zone was then analyzed against their postoperative ages.
The radioactivity regressed to Grade 1 or 2 from Grade 4 or 5 within 12 months after cementless total hip replacement in 87.5% and 93.8% of patients in zones 2 and 4, respectively. Even though the radioactivity within zones 1, 3, and 5 tended to decrease, persistent elevation of activity (over grade 2) lasted up to 12 months after surgery in 31% or 37% of the patients.
The radioactivity after cementless total hip replacement tended to regress in proportion to the postimplant age. The regression rate varied depending on the periprosthetic zones.
评估在接受非骨水泥型全髋关节置换术的无症状患者中,连续进行锝-99m亚甲基二膦酸盐(Tc-99m MDP)扫描时放射性的分布及程度,以诊断术后松动情况。
对于使用Harris Galante非骨水泥型假体进行全髋关节置换的患者,尽可能每三个月进行一次Tc-99m MDP扫描,持续一年。共获得45例患者的83次扫描结果。使用任意的5分制分级系统评估假体周围五个区域(区域1:大转子;2:假体外侧柄;3:假体尖端;4:假体内侧柄;5:小转子)的摄取情况。1级表示摄取正常,5级表示摄取最高。然后分析每个区域摄取的分级与其术后年龄的关系。
在非骨水泥型全髋关节置换术后12个月内,分别有87.5%和93.8%的患者在区域2和区域4中,放射性从4级或5级降至1级或2级。尽管区域1、3和5内的放射性有下降趋势,但在术后12个月内,仍有31%或37%的患者活动持续升高(超过2级)。
非骨水泥型全髋关节置换术后的放射性倾向于随着植入后年龄的增长而回归。回归速率因假体周围区域而异。