Weaver K, Siantar C H, Chandler W, White R M
Department of Radiation Oncology, University of California, San Francisco 94143, USA.
Med Phys. 1996 Dec;23(12):2079-84. doi: 10.1118/1.597890.
Monte Carlo techniques have the potential for producing accurate brachytherapy dose distributions in heterogeneous finite geometries. However, for routine clinical use, computational speed must be adequate. A fast, all-particle, CT-based Monte Carlo code called PEREGRINE is being developed at Lawrence Livermore National Laboratory for radiation treatment planning. As one feature, the code will produce accurate dose distributions from brachytherapy sources in heterogeneous geometries. For efficiency, brachytherapy sources in this model are treated as points or line segments. Radiation is emitted with the proper energy spectrum and (perhaps anisotropic) angular distribution. In particular, for anisotropic emission the polar angle is determined by a random-number driven empirical function constructed from a source's measured or precomputed fluence emission pattern. Source model parameters are presented for iodine and iridium sources. While designed for the PEREGRINE program, this source model can be used in any Monte Carlo code.
蒙特卡罗技术有潜力在非均匀有限几何结构中生成精确的近距离放射治疗剂量分布。然而，对于常规临床应用，计算速度必须足够快。劳伦斯利弗莫尔国家实验室正在开发一种名为“游隼”的基于CT的快速全粒子蒙特卡罗代码，用于放射治疗计划。作为一个特点，该代码将在非均匀几何结构中从近距离放射治疗源生成精确的剂量分布。为提高效率，此模型中的近距离放射治疗源被视为点或线段。辐射以适当的能谱和（可能各向异性的）角分布发射。特别是对于各向异性发射，极角由根据源的测量或预先计算的注量发射模式构建的随机数驱动经验函数确定。给出了碘源和铱源的源模型参数。虽然该源模型是为“游隼”程序设计的，但可用于任何蒙特卡罗代码。
