Alimov Kh A, Monasypova I Kh
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(5):711-4.
The clinico-follow-up study of 90 patients with recurrent schizophrenia with an early onset (up to 20 years) permitted to depict peculiarities of the clinical picture and the course at a remote period of the disease depending upon the clinical manifestations of the previous stage and the degree of the progressiveness. An analysis of the clinical material has demonstrated that periodic schizophrenic with an early onset contains, as well as in adults, various variants of the course that differ in the degree of progressiveness (mild cyclothimuc, reduced, "cliche" and complicated states) which most likely condition a different level of "outcome": from the mild ones on the level of psychic asthenia up to more expressed in the form of personality autization of a different degree. The stated negative symptomatology was determined on the background of asthenical remission of a combined character (affective and asthenical disorders).
对90例早发性(发病年龄至20岁)复发性精神分裂症患者的临床随访研究,得以根据疾病前一阶段的临床表现和进展程度,描绘出疾病远期的临床特征和病程特点。对临床资料的分析表明,早发性周期性精神分裂症患者与成年患者一样,存在不同进展程度(轻度循环性情感气质型、减退型、“刻板”型和复杂型)的病程变异,这些变异很可能导致不同水平的“结局”:从精神衰弱水平的轻度变异到不同程度人格衰退形式的更明显变异。上述阴性症状是在伴有情感和衰弱障碍的混合性衰弱缓解背景下确定的。