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使用球囊扩张式和自膨式支架的经颈静脉肝内门体分流术(TIPS):3年半经验后的技术和临床情况

Transjugular intrahepatic portosystemic shunting (TIPS) with balloon-expandable and self-expanding stents: technical and clinical aspects after 3 1/2 years' experience.

作者信息

Tesdal I K, Jaschke W, Bühler M, Adamus R, Filser T, Holm E, Georgi M

机构信息

Institut für Klinische Radiologie, Klinikum Mannheim, Universität Heidelberg, Germany.

出版信息

Cardiovasc Intervent Radiol. 1997 Jan-Feb;20(1):29-37. doi: 10.1007/s002709900105.

Abstract

PURPOSE

To evaluate prospectively our experience with transjugular intrahepatic portosystemic shunt (TIPS) using four different metallic stents.

METHODS

Between November 1991 and April 1995, 57 patients (41 men and 16 women; age 35-72 years, mean 54 years) underwent the TIPS procedure. Techniques for portal vein localization before and during TIPS were fluoroscopy, computed tomography (CT) studies, wedged hepatic venography, arterial portography, and ultrasound. After predilation we deployed balloon-expandable (n = 48) and self-expanding (n = 45) metallic stents. Fifteen patients underwent variceal embolization. Initial follow-up angiograms (mean 6.9 months, range 3-24 months) were obtained in 39 of these patients.

RESULTS

Fifty-three patients (93%) had successful TIPS placement. The mean decrease in portal pressure was 42.7%. Besides fluoroscopy, the most helpful techniques for portal vein localization were venography and CT. Residual stenosis (n = 1) and late shortening (n = 4) of Wallstents resulted in shunt dysfunction. The technical problems encountered with the Palmaz stent resulted from its lack of flexibility. We combined balloon-expandable and self-expanding stents in 12 patients. The 30-day and late follow-up (mean 11.9 months) percutaneous reintervention rates were 11.3% and 64.2%, respectively. There were no clinically significant complications related to the TIPS insertions.

CONCLUSION

An ideal stent does not exist for TIPS, and the authors recommend combining a Palmaz stent with a flexible self-expanding stent.

摘要

目的

前瞻性评估我们使用四种不同金属支架进行经颈静脉肝内门体分流术(TIPS)的经验。

方法

1991年11月至1995年4月期间,57例患者(41例男性和16例女性;年龄35 - 72岁,平均54岁)接受了TIPS手术。TIPS术前及术中门静脉定位技术包括荧光透视、计算机断层扫描(CT)、楔形肝静脉造影、动脉门静脉造影和超声检查。预扩张后,我们置入了球囊扩张式(n = 48)和自膨式(n = 45)金属支架。15例患者接受了曲张静脉栓塞术。其中39例患者获得了初始随访血管造影(平均6.9个月,范围3 - 24个月)。

结果

53例患者(93%)成功置入TIPS。门静脉压力平均下降42.7%。除荧光透视外,对门静脉定位最有帮助的技术是静脉造影和CT。Wallstents支架的残余狭窄(n = 1)和后期缩短(n = 4)导致分流功能障碍。Palmaz支架遇到的技术问题源于其缺乏柔韧性。我们在12例患者中联合使用了球囊扩张式和自膨式支架。30天及后期随访(平均11.9个月)的经皮再干预率分别为11.3%和64.2%。未出现与TIPS置入相关的具有临床意义的并发症。

结论

不存在适用于TIPS的理想支架,作者建议将Palmaz支架与柔韧性好的自膨式支架联合使用。

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