有丝分裂：别生气，要摆平。
Mitosis: don't get mad, get even.
作者信息
Glotzer M
机构信息
Cell Biology Program, European Molecular Biology Laboratory, Heidelberg, Germany.
出版信息
Curr Biol. 1996 Dec 1;6(12):1592-4. doi: 10.1016/s0960-9822(02)70781-1.
PMID:8994822
Abstract
The 'mitotic spindle checkpoint' ensures that, before a cell exits from mitosis, all of its chromosomes are aligned on the spindle to form the metaphase plate. Mad2 is an essential component of this checkpoint system and it binds specifically to unattached kinetochores.
摘要
“有丝分裂纺锤体检查点”可确保在细胞退出有丝分裂之前，其所有染色体都在纺锤体上排列，形成中期板。Mad2是该检查点系统的一个重要组成部分，它特异性地结合未附着的动粒。
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