Desreumaux P, Capron M
Clinique des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, University Hospital, Lille, France.
Curr Opin Immunol. 1996 Dec;8(6):790-5. doi: 10.1016/s0952-7915(96)80006-9.
Mainly located in the skin or mucosa of patients with allergic diseases, eosinophils contribute directly to tissue damage and chronic inflammation. The past year has seen significant advances in the study of the factors involved in the specific tissue recruitment of eosinophils, including chemoattractants and their receptors. New data have been obtained on the synthesis by eosinophils of various cytokines mostly released by immune complexes.
嗜酸性粒细胞主要存在于过敏性疾病患者的皮肤或黏膜中,直接导致组织损伤和慢性炎症。过去一年,在嗜酸性粒细胞特异性组织募集相关因素的研究方面取得了重大进展,这些因素包括趋化因子及其受体。关于嗜酸性粒细胞合成多种主要由免疫复合物释放的细胞因子,也获得了新的数据。