对于肾移植和肝移植儿童，在开始重组人生长激素（rhGH）治疗前无需进行激发性生长激素检测。
Provocative growth hormone testing is not required before initiation of rhGH treatment in children with renal and liver transplants.
作者信息
Sarna S, Ronnholm K, Sipila I, Holmberg C
机构信息
Children's Hospital, University of Helsinki, Finland.
出版信息
Br J Clin Pract Suppl. 1996 Aug;85:41-3.
PMID:8995029
Abstract
GH provocative testing does not predict subsequent growth response, and is not therefore required before initiation of rhGH treatment in children with renal and liver transplants. However, therapeutic doses of glucocorticoids may potentially inhibit GH secretion in some patients, and determining GH secretory status by provocation tests and measuring spontaneous GH secretion is advisable at some point after organ Tx to exclude GH deficiency.
摘要
生长激素激发试验无法预测后续的生长反应，因此在肾移植和肝移植患儿开始使用重组人生长激素治疗前无需进行该试验。然而，治疗剂量的糖皮质激素可能会在某些患者中抑制生长激素分泌，因此在器官移植后的某个时间点，通过激发试验确定生长激素分泌状态并测量自发性生长激素分泌，以排除生长激素缺乏是可取的。
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