Martirosian V V, Chilikin L A
Zh Vopr Neirokhir Im N N Burdenko. 1977 Jul-Aug(4):43-7.
Study of the daily thythms of free 17-oxycorticosteroids in blood plasma of patients with tumors of the spinal cord and spine, discogenic pain syndrome, and of those who underwent plastic surgery for cranial defects revealed disturbances in the biorhythms of the adrenal cortex in patients with tumors of the spinal cord before operation. The postoperative period in all patients was characterized by the development of a stress reaction and paradoxical-type curves of the daily content of these hormones on the 3rd day with complete restoration of adrenal cortex biorhythms by the 15th day. The patients examined did not require special hormonotherapy.
对患有脊髓和脊柱肿瘤、椎间盘源性疼痛综合征的患者以及接受颅骨缺损整形手术的患者血浆中游离17-氧皮质类固醇的每日节律进行研究发现，脊髓肿瘤患者术前肾上腺皮质的生物节律存在紊乱。所有患者的术后阶段均表现为应激反应的出现以及这些激素每日含量在第3天呈反常型曲线，到第15天肾上腺皮质生物节律完全恢复。所检查的患者无需特殊激素治疗。
