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正常大鼠及单侧前庭神经横断后内侧和下行前庭核的精细结构

Fine structure of the medial and descending vestibular nuclei in normal rats and after unilateral transection of the vestibular nerve.

作者信息

Schwarz D W, Schwarz I E, Fredrickson J M

出版信息

Acta Otolaryngol. 1977 Jul-Aug;84(1-2):80-90. doi: 10.3109/00016487709123945.

DOI:10.3109/00016487709123945
PMID:899755
Abstract

Cells and neuropil are of similar structure in the descending and medial vestibular nuclei. Two cell types were found: small neurons and larger cells. Three types of axon terminals have been defined: small and large terminals containing spherical vesicles (SV) and terminals with elongated vesicles (EV). Small SV terminals contact perikarya and dendrites, whereas large SV terminals contact fine dendritic branches. EV terminals contact neurons at perikarya and large as well as small dendritic profiles. SV terminals can be presynaptic to EV terminals. Vestibular nerve transection resulted in degeneration of small SV terminals which were found from the first to fifth postoperative day in the ipsilateral nuclei. Glycogen granules were found in various types of axon terminals bilaterally in the vestibular nuclei 3-5 days after right vestibular transection. They were not observed in normal animals or in degenerating vestibular afferent terminals.

摘要

在下行和内侧前庭核中,细胞和神经纤维网结构相似。发现了两种细胞类型:小神经元和较大的细胞。已确定三种轴突终末类型:含有球形囊泡(SV)的小终末和大终末,以及含有细长囊泡(EV)的终末。小SV终末与胞体和树突接触,而大SV终末与细小的树突分支接触。EV终末在胞体以及大小树突轮廓处与神经元接触。SV终末可以是EV终末的突触前终末。前庭神经横断导致小SV终末变性,在同侧核中于术后第1天至第5天发现这种变性。右侧前庭横断3 - 5天后,在前庭核双侧的各种轴突终末中发现糖原颗粒。在正常动物或变性的前庭传入终末中未观察到糖原颗粒。

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