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[布基纳法索博博迪乌拉索市四分之一城区疟疾暴发的影响]

[Effects of malaria outbreak in a quarter of the city of Bobo-Dioulasso (Burkina Faso)].

作者信息

Gazin P P, Gonçalves K, Koné B, Lochouarn L

机构信息

ORSTOM, Centre Muraz, Bobo-Dioulasso (Burkina Faso).

出版信息

Bull Soc Pathol Exot. 1996;89(3):200-3.

PMID:8998415
Abstract

Weekly malaria attack incidence rate has been studied from June to September 1993 in a cluster of children and adults living in a quarter of the city of Bobo-Dioulasso (Burkina Faso). The city is located in the savanna area with an average of 1000 mm rainfall in five months. In this recently built quarter at the outskirts, yearly average malaria transmission was of four infected bites mainly due to Anopheles gambiae. The medical team visited each week each included family (28 families, 290 persons). Malaria attack has been defined as a fever attack or the certitude of fever during the hours before, with clinical malaria-related signs, a patent parasitaemia and the lack of obvious other etiology. Parasitic density threshold of 2000 PRBC/mm3 for the children and adolescents, till 16 years old and of 1,000 PRBC/mm3 for the adults, have been utilized for the definition of unquestionable malaria attack. 4128 medical observations have been done. 17 unquestionable malaria attacks have been observed in infants, children and adults with parasitic densities from 40,000 to 720,000 PRBC/mm3. 18 likely attacks were also observed with clinical signs but low density of Plasmodium. All were induced by P. falciparum. From June to the end of July the weekly incidence rate was five for one thousand and from August twelve for one thousand. In a place with a low transmission, the success of an infection is higher than in places with an intense transmission. This observation is of some importance for the control of the disease by reduction of the transmission.

摘要

1993年6月至9月,对居住在布基纳法索博博迪乌拉索市某一区的一群儿童和成年人的疟疾周发病率进行了研究。该市位于热带稀树草原地区,五个月的平均降雨量为1000毫米。在这个位于郊区的新建区域,每年平均疟疾传播率为每四人中有一人被感染,主要是由冈比亚按蚊传播。医疗团队每周走访每个纳入的家庭(28个家庭,290人)。疟疾发作被定义为发热发作,或在发作前数小时确定有发热,并伴有与疟疾相关的临床体征、明显的寄生虫血症且无其他明显病因。对于16岁及以下的儿童和青少年,确定无疑的疟疾发作的寄生虫密度阈值为2000个疟原虫/立方毫米,成年人的阈值为1000个疟原虫/立方毫米。共进行了4128次医学观察。在婴儿、儿童和成年人中观察到17次确定无疑的疟疾发作,寄生虫密度为40000至720000个疟原虫/立方毫米。还观察到18次可能的发作,有临床症状但疟原虫密度较低。所有发作均由恶性疟原虫引起。6月至7月底,周发病率为千分之五,8月为千分之十二。在一个传播率较低的地方,感染成功的几率高于传播强烈的地方。这一观察结果对于通过减少传播来控制该疾病具有一定重要性。

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