Sabatelli M, Mignogna T, Lippi G, Porcu C, Tonali P
Neurological Institute and UILDM, Catholic University, Rome, Italy.
Clin Neuropathol. 1996 Jan-Feb;15(1):17-21.
We describe a patient affected by chronic inflammatory demyelinating polyneuropathy (CIDP) whose sural nerve biopsy revealed a marked edema of the myelin sheath. Since this change has been previously described in human peripheral nerves only in CIDP patients, we suggest that intramyelinic edema may have a role in the pathogenesis of demyelinating neuropathies.