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尼古拉斯·安德里奖:骨水泥型与非骨水泥型全髋关节置换术的对比结果

The Nicolas Andry award: comparative results of cemented and cementless total hip arthroplasty.

作者信息

Rorabeck C H, Bourne R B, Mulliken B D, Nayak N, Laupacis A, Tugwell P, Feeney D

机构信息

University Hospital, London, Ontario, Canada.

出版信息

Clin Orthop Relat Res. 1996 Apr(325):330-44.

PMID:8998896
Abstract

A prospective randomized clinical trial comparing cemented to cementless total hip arthroplasty has been ongoing at the author's institution since 1987. All parameters assessed showed that there was no statistically significant difference in any of the health related quality of life measures used when patients with cement were compared with patients without cement at any of the followup periods as many as 4 years later. The improvement was dramatic and sustained. No components (cemented or cementless) have been revised to date (average, 4.8 years). A radiographic analysis showed probable loosening of the cemented socket in 24% and presumed minimal pelvic osteolysis in 8%. The cementless sockets showed a greater frequency and severity of pelvic osteolysis (14%). The cemented femoral component was judged to be possibly loose in 10%; however, none were considered probably loose. The patients who had cementless femoral components were doing extremely well with the components showing very little subsidence or proximal stress protection noted. Osteolysis on the femoral side was not seen in any of the cementless stems. Total hip replacement gives comparable clinical results when health related quality of life measures are analyzed; however, metal backed cemented acetabular components have a high rate of radiographic failure. Short-term stability of a non-cemented porous coated titanium stem, however, gave excellent clinical and radiographic results.

摘要

自1987年起,作者所在机构一直在进行一项比较骨水泥型与非骨水泥型全髋关节置换术的前瞻性随机临床试验。所有评估参数显示,在长达4年的任何随访期内,使用骨水泥的患者与未使用骨水泥的患者相比,在任何与健康相关的生活质量测量指标上均无统计学显著差异。改善效果显著且持续。迄今为止(平均4.8年),没有任何部件(骨水泥型或非骨水泥型)进行翻修。影像学分析显示,24%的骨水泥臼杯可能出现松动,8%的患者推测有轻微骨盆骨溶解。非骨水泥臼杯出现骨盆骨溶解的频率和严重程度更高(14%)。10%的骨水泥股骨部件被判定可能松动;然而,没有一个被认为很可能松动。使用非骨水泥股骨部件的患者情况非常好,部件显示出极少的下沉或近端应力遮挡。在任何非骨水泥柄中均未观察到股骨侧骨溶解。当分析与健康相关的生活质量指标时,全髋关节置换术的临床结果相当;然而,金属背衬骨水泥髋臼部件的影像学失败率很高。然而,非骨水泥多孔涂层钛柄的短期稳定性给出了出色的临床和影像学结果。

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