Gabutti L, Mombelli G
Reparto di Medicina Interna, Ospedale regionale di Lacarno.
Schweiz Med Wochenschr. 1996 Dec 7;126(49):2130-5.
This retrospective study analyzes and compares the incidence of admissions for alcohol and drug (i.e.: heroin and cocaine) induced diseases to the internal medicine service of Locarno Regional Hospital (61 beds plus intensive care unit) between January 1, 1993 and December 31, 1994. Of 4038 admissions, 298 (7.4%) were related to alcoholism and drug addiction. 4.2% of all hospital days were due to alcohol abuse, whereas 3.2% were related to drug abuse (of these 1.8% were for HIV-associated diseases and 0.9% for withdrawal treatment). The male/female ratio was 3:1 in both groups, the average age of women being significantly lower in the alcoholic group (50.5 +/- 14.4 years vs. 58.1 +/- 12.9; p = 0.003). Over 90% of the patients with alcohol-induced conditions continued to consume alcohol. On the contrary, only 16% of the HIV-positive patients were still drug-addicted. The in-hospital mortality was 6% (5% in the alcoholic group; 1.6% and 12%, respectively, in the HIV-negative and HIV-positive groups of drug addicts). This study confirms the high prevalence of diseases related to alcohol and drug abuse. Women are less affected, but show complications of alcohol abuse earlier. Despite the HIV epidemic in our area, the admissions of alcoholics to the hospital are more frequent than those of drug addicts. Most of the drug addicts with an HIV-associated condition are in remission, whereas alcoholics with alcohol-induced diseases continue, for the most part, to be alcohol-dependent.
这项回顾性研究分析并比较了1993年1月1日至1994年12月31日期间,洛迦诺地区医院内科(61张床位加重症监护病房)收治的酒精和药物(即海洛因和可卡因)所致疾病的发生率。在4038例住院病例中,298例(7.4%)与酒精中毒和药物成瘾有关。所有住院天数的4.2%是由酒精滥用所致,而3.2%与药物滥用有关(其中1.8%是与HIV相关疾病,0.9%是用于戒毒治疗)。两组的男女比例均为3:1,酒精中毒组女性的平均年龄显著低于药物成瘾组(50.5±14.4岁对58.1±12.9岁;p=0.003)。超过90%的酒精所致疾病患者继续饮酒。相反,只有16%的HIV阳性患者仍有药物成瘾。住院死亡率为6%(酒精中毒组为5%;药物成瘾的HIV阴性和HIV阳性组分别为1.6%和12%)。本研究证实了与酒精和药物滥用相关疾病的高患病率。女性受影响较小,但酒精滥用的并发症出现得更早。尽管我们地区有HIV疫情,但酒精中毒患者入院的频率高于药物成瘾者。大多数患有与HIV相关疾病的药物成瘾者病情缓解,而患有酒精所致疾病的酒精中毒者在很大程度上仍依赖酒精。