Müller R J, Asseryanis E, Wieser F, Schurz B
Universitätsfrauenklinik Wien.
Ultraschall Med. 1996 Aug;17(4):163-6. doi: 10.1055/s-2007-1003173.
This study investigates the reliability of ultrasonographic screenings for detecting fetal malformations in pregnancy. The data from 1505 screening examinations of pregnant women who underwent routine checks at the Department of Obstetrics of the University of Vienna, were compared with the anomalies diagnosed in the newborn of the same collective. Fetal malformations were diagnosed in 28 screening cases. The statistical distribution of these anomalies is shown for the different organ systems. In 5 newborn malformations were found, which had not been diagnosed sonographically. Another 23 newborn had minor malformations in regions that are not included in the routine screening ultrasound. The results show a high accuracy of the sonographic screening examination, with the exception of the median facial region and the large vessels of the base of the heart. The fact that not all of the cardiac malformations were diagnosed prompts the performance of an extended sonographic inspection of the fetal heart within the framework of routine screening.
本研究调查了超声筛查在孕期检测胎儿畸形方面的可靠性。将维也纳大学妇产科接受常规检查的1505名孕妇的筛查数据，与同一群体新生儿诊断出的异常情况进行了比较。在28例筛查病例中诊断出胎儿畸形。这些畸形在不同器官系统中的统计分布情况已列出。在新生儿中发现了5例畸形，这些畸形在超声检查中未被诊断出来。另外23例新生儿在常规筛查超声未涵盖的区域存在轻微畸形。结果表明，除了面部中部区域和心脏底部大血管外，超声筛查检查具有较高的准确性。并非所有心脏畸形都能被诊断出来这一事实，促使在常规筛查框架内对胎儿心脏进行扩展超声检查。
