Albrecht A, Deutinger J, Stümpflen I, Beck S, Bernaschek G
Abteilung für Pränatale Diagnostik u. Therapie der Universitäts-Frauenklinik Wien.
Ultraschall Med. 1996 Aug;17(4):171-4. doi: 10.1055/s-2007-1003175.
To investigate the influence of cordocentesis with or without blood transfusion on umbilical and fetal blood flow characteristics.
Of 42 pregnant women suffering from Rh. incompatibility 15 had a puncture of the umbilical cord for diagnostic reasons only. In 27 cases a total of 86 punctures was done for blood transfusion. Fetal heart rate, umbilical artery A/B Ratio and Pulsatility Index (PI) in the fetal aorta were measured before and after cordocentesis in all cases having or having not a transfusion.
Diagnostic and therapeutic cordocentesis resulted in a slight decrease of peripheral resistance. Significant differences were only observed in cases with a haematocrit < 20% compared to cases with values > 40% or if the final haematocrit after transfusion resulted in a value of < 30%.
The decrease peripheral resistance in cases of therapeutic cordocentesis can be attributed to the increase in blood volume and sufficient oxygenation of blood improving fetal perfusion. Doppler sonography is not helpful in the clinical management of red blood cell immunisation.
探讨脐带穿刺术(无论是否输血)对脐血流和胎儿血流特征的影响。
42例患有Rh血型不合的孕妇中,15例仅因诊断目的进行脐带穿刺。27例共进行了86次输血脐带穿刺。在所有进行或未进行输血的病例中,在脐带穿刺前后测量胎儿心率、脐动脉A/B比值和胎儿主动脉搏动指数(PI)。
诊断性和治疗性脐带穿刺导致外周阻力略有降低。与血细胞比容>40%的病例相比,仅在血细胞比容<20%的病例中观察到显著差异,或者输血后最终血细胞比容<30%时观察到显著差异。
治疗性脐带穿刺时外周阻力降低可归因于血容量增加和血液充分氧合改善了胎儿灌注。多普勒超声检查对红细胞免疫的临床管理没有帮助。