Lyle W M, Bobier W R
Am J Optom Physiol Opt. 1977 May;54(5):276-81. doi: 10.1097/00006324-197705000-00002.
Pupil responses to phenylephrine alone and to phenylephrine preceded by a topical anesthetic were recorded by means of an infrared pupillometer. In response to phenylephrine, pupils dilated more in eyes with pale irides. Dilation was greater if a topical anesthetic was applied before the mydriatic. Benoxinate, proparacaine, and tetracaine produced approximately equal degrees of enhancement of the mydriasis. One drop of 1% phenylephrine had only a small dilating effect on an eye when the fellow eye received the phenylephrine preceded by 0.5% proparacaine.
通过红外瞳孔计记录单独使用去氧肾上腺素以及在局部麻醉药预处理后使用去氧肾上腺素时的瞳孔反应。对去氧肾上腺素的反应中，虹膜颜色浅的眼睛瞳孔扩张更明显。如果在使用散瞳药之前应用局部麻醉药，瞳孔扩张会更显著。丁氧苯卡因、丙美卡因和丁卡因产生的散瞳增强程度大致相同。当另一只眼睛先接受0.5%丙美卡因预处理，再使用去氧肾上腺素时，一滴1%去氧肾上腺素对该眼的散瞳作用很小。
