The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization.
作者信息
Ishwad C S, Shriver M D, Lassige D M, Ferrell R E
机构信息
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA.
出版信息
Hum Genet. 1997 Jan;99(1):103-5. doi: 10.1007/s004390050320.
PMID:9003504
Abstract
We have identified a highly informative dinucleotide repeat in the 5'-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18-37 copies of a (CT) repeat with an observed heterozygosity of 82-83% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13-15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.
摘要
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