Tsang I S, Katz V L, Wells S D
Department of OB/GYN, UNC School of Medicine, Eugene, OR, USA.
Int J Gynaecol Obstet. 1996 Dec;55(3):231-5. doi: 10.1016/s0020-7292(96)02778-6.
This study sought to evaluate maternal characteristics and pregnancy outcomes among women with hyperemesis gravidarum.
We performed a retrospective analysis of pregnancy records of obstetric admissions during a 6-year period. Women treated as out-patients for hyperemesis were also identified. Hyperemesis was defined as excessive nausea and vomiting resulting in dehydration, extensive medical therapy, and/or hospital admission. Statistical analysis was by t-test and chi square.
We identified 193 women (1.5%) who developed hyperemesis among 13,053 women. Racial status, marital status, age, and gravidity were similar between the hyperemesis patients and the general population. However, there were less women with hyperemesis who were para 3 or greater. Forty-six women (24%) required hospitalization for hyperemesis, mean hospital stay 1.8 days, range 1-10 days. One patient required parenteral nutrition, two had yeast esophagitis, none had HIV infection, psychiatric pathology or thyroid disease. Pregnancy outcomes between hyperemesis patients and the general population were similar for mean birth weight, mean gestational age, deliveries less than 37 weeks, Apgar scores, perinatal mortality or incidence of fetal anomalies. Our incidence of hyperemesis (1.5%) is similar to that of other published reports.
Women with hyperemesis have similar demographic characteristics to the general obstetric population, and have similar obstetric outcomes.
本研究旨在评估妊娠剧吐女性的母体特征及妊娠结局。
我们对6年期间产科住院患者的妊娠记录进行了回顾性分析。还确定了作为门诊患者接受妊娠剧吐治疗的女性。妊娠剧吐定义为严重恶心和呕吐导致脱水、广泛的药物治疗及/或住院治疗。采用t检验和卡方检验进行统计分析。
在13053名女性中，我们确定了193名（1.5%）发生妊娠剧吐的女性。妊娠剧吐患者与普通人群在种族状况、婚姻状况、年龄和妊娠次数方面相似。然而，妊娠次数为3次及以上的妊娠剧吐女性较少。46名女性（24%）因妊娠剧吐需要住院治疗，平均住院时间1.8天，范围为1 - 10天。1名患者需要肠外营养，2名患有酵母菌食管炎，无人感染HIV、有精神病理问题或甲状腺疾病。妊娠剧吐患者与普通人群的妊娠结局在平均出生体重、平均孕周、孕周小于37周的分娩、阿氏评分、围产儿死亡率或胎儿畸形发生率方面相似。我们的妊娠剧吐发生率（1.5%）与其他已发表报告的发生率相似。
妊娠剧吐女性的人口统计学特征与普通产科人群相似，且产科结局也相似。
