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[透析患者结膜和角膜的变化]

[Changes in the conjunctiva and cornea in dialyzed patients].

作者信息

Stibor V, Lachmanová J, Povýsil C

机构信息

II. ocní klinika 1. LF UK, Praha.

出版信息

Cesk Slov Oftalmol. 1996 Oct;52(5):286-90.

PMID:9005047
Abstract

The author examined 119 patients having regular dialyzation treatment and a control group of 90 healthy subjects, divided into groups by decades. Depending on the intensity of pathological changes, they created four categories; the fifth comprised normal findings. The prepared from the bioptic material of the conjunctiva of two patients preparations which were examined for calcium and amyloid deposits. Pathological changes were found in 74.8%. The authors try to explain the cause of conjunctival and corneal changes, consistent with the theory of hastened ageing in chronic renal failure of patients treated by regular haemodialysis. The so far unique findings of amyloid of the conjunctiva could be possibly used in future for the diagnosis of amyloidosis instead biopsies.

摘要

作者检查了119名接受定期透析治疗的患者以及90名健康受试者组成的对照组,并按年龄段分组。根据病理变化的程度,他们划分出四类;第五类为正常结果。从两名患者结膜的活检材料制备了样本,检测其中的钙和淀粉样沉积物。发现74.8%的患者存在病理变化。作者试图解释结膜和角膜变化的原因,这与接受定期血液透析治疗的慢性肾衰竭患者加速衰老的理论相符。结膜淀粉样变这一迄今独特的发现未来可能用于替代活检来诊断淀粉样变性。

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