[The use of the antioxidant trimetazidine (Preductal) in the combined therapy of acute myocardial infarct].

86 patients with acute transmural and macrofocal myocardial infarction received combined treatment which included standard therapy (thrombolytic drugs, beta-blockers, APP inhibitors, nitrates, aspirin) and antioxidant trimetasidine. The addition of the latter was beneficial: the size of the myocardial lesion was limited, electrical instability of the heart attenuated, early dilatation of the left heart prevented.