Yasunaga Y, Ochi M, Ikuta Y, Shimogaki K, Dohi D
Department of Orthopaedic Surgery, Hiroshima University School of Medicine, Japan.
Arch Orthop Trauma Surg. 1997;116(1-2):74-6. doi: 10.1007/BF00434105.
We investigated the morphological changes in the articular cartilage after rotational acetabular osteotomy in 16 adolescent rabbits. Radiological and histological studies were conducted at 12 and 24 weeks postoperatively. The radiological evaluations at 12 and 24 weeks showed significantly increased femoral head coverage. No cases of osteonecrosis of the acetabulum or femoral head nor narrowing of the joint space was observed. The histology of the articular cartilage at 12 weeks postoperatively showed cloning and hypercellularity of the chondrocytes in the medial portion of the acetabular roof, indicating remodelling due to the increased weight-bearing stress caused by the osteotomy. The histology at 24 weeks postoperatively showed less cloning of the chondrocytes, indicating that the remodelling process in the articular cartilage induced by this procedure was almost complete at 24 weeks. Degeneration of the articular cartilage was not observed within 24 weeks of the operation.
我们研究了16只青春期兔行髋臼旋转截骨术后关节软骨的形态学变化。在术后12周和24周进行了影像学和组织学研究。术后12周和24周的影像学评估显示股骨头覆盖明显增加。未观察到髋臼或股骨头坏死病例，也未观察到关节间隙变窄。术后12周关节软骨组织学显示髋臼顶内侧部分软骨细胞克隆和细胞增多，表明由于截骨导致负重应力增加而发生重塑。术后24周组织学显示软骨细胞克隆减少，表明该手术诱导的关节软骨重塑过程在24周时几乎完成。术后24周内未观察到关节软骨退变。
