The immune system in severe ovarian hyperstimulation syndrome.

Recently, evidence has accumulated concerning the interaction between the immune and reproductive systems that results from sharing certain lymphohematopoietic cytokines and their receptors. Furthermore, several cytokines have been implicated as having a role in the prediction and pathophysiology of ovarian hyperstimulation syndrome (OHSS). The hitherto known studies concerning the role of the immune system in OHSS, together with a hypothesis regarding the role of interleukin-2 as a possible culprit of this complication, are presented.