Rappaport Z H
Department of Neurosurgery, Rabin Medical Center, Petah Tikva, Israel.
Isr J Med Sci. 1996 Dec;32(12):1232-4.
Trigeminal neuralgia stands out as one of the few severe neuropathic pain states for which successful treatment options are available. Up to one-half of patients become refractory to medical therapy over time. At this point, the question of which intervention is appropriate becomes an important issue. A personal series of 150 patients treated between 1988 and 1995 is reviewed. Patients under 65 years and in good general health underwent surgery for microvascular decompression of the trigeminal root; in the remaining 120 patients glycerol was injected percutaneously into the trigeminal cistern. The results in these two patient groups is presented and the rationale of choosing an operative versus a percutaneous procedure is discussed in light of the outcome in this series and in the literature.
三叉神经痛是少数几种有成功治疗方案的严重神经性疼痛状态之一。随着时间的推移，多达一半的患者会对药物治疗产生耐药性。此时，选择何种干预措施成为一个重要问题。本文回顾了1988年至1995年间治疗的150例患者的个人病例系列。65岁以下且总体健康状况良好的患者接受了三叉神经根微血管减压手术；其余120例患者经皮向三叉神经池注射甘油。本文展示了这两组患者的治疗结果，并根据本病例系列及文献中的结果，讨论了选择手术治疗与经皮治疗的理由。
