Tang S F, Miller O I
Department of Intensive Care, Royal Alexandra Hospital for Children, Westmead, Australia.
J Paediatr Child Health. 1996 Dec;32(6):539-41. doi: 10.1111/j.1440-1754.1996.tb00970.x.
Inhaled nitric oxide is currently being investigated as a selective pulmonary vasodilator for neonates with persistent pulmonary hypertension. The use of continuous inhaled nitric oxide during emergency transportation of three critically III neonates with meconium aspiration and pulmonary hypertension is described. The successful application of this technique may allow safer transportation of neonates who require high level intensive care including ongoing nitric oxide, high frequency ventilation and/or extracorporeal life support. Regionally based nitric oxide-equipped retrieval teams may relieve the pressure on smaller neonatal intensive care units to provide inhaled nitric oxide therapy and allow centralization of nitric oxide resources, thus facilitating development of expertise and the completion of meaningful research programs with substantial recruitment.
吸入一氧化氮目前正作为一种选择性肺血管扩张剂用于患有持续性肺动脉高压的新生儿进行研究。本文描述了在三名患有胎粪吸入和肺动脉高压的危重新生儿紧急转运期间持续吸入一氧化氮的应用情况。这项技术的成功应用可能使那些需要高水平重症监护（包括持续使用一氧化氮、高频通气和/或体外生命支持）的新生儿得到更安全的转运。配备一氧化氮的区域性转运团队可以减轻小型新生儿重症监护病房提供吸入一氧化氮治疗的压力，并使一氧化氮资源得以集中，从而有助于专业技能的发展以及开展有大量受试者参与的有意义的研究项目。
