肾缺血对梗阻性黄疸大鼠的影响。
Effect of renal ischaemia in rats with obstructive jaundice.
作者信息
Craddock G N, Lee E
出版信息
Ann R Coll Surg Engl. 1977 Sep;59(5):409-14.
Abstract
The ability of kidneys to withstand renal ischaemia has been tested in jaundiced and non-jaundiced rats. No significant difference could be demonstrated between the two groups of animals except that renal weight increased greatly in the presence of jaundice. Both jaundiced and non-jaundiced animals showed a median lethal dose of renal ischaemia of approximately 120 min when renal function was tested by delayed opposite nephrectomy. It was shown that a recent laparotomy renders the kidney more susceptible to renal ischaemia.
摘要
已在黄疸和非黄疸大鼠中测试了肾脏耐受肾缺血的能力。除了在黄疸情况下肾脏重量大幅增加外，两组动物之间未显示出显著差异。当通过延迟对侧肾切除术测试肾功能时，黄疸和非黄疸动物的肾缺血中位致死剂量均约为120分钟。结果表明，近期的剖腹手术会使肾脏更容易受到肾缺血的影响。
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