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Mutator specificity and disease: looking over the FENce.

作者信息

Kunkel T A, Resnick M A, Gordenin D A

机构信息

Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

出版信息

Cell. 1997 Jan 24;88(2):155-8. doi: 10.1016/s0092-8674(00)81832-2.

DOI:10.1016/s0092-8674(00)81832-2
PMID:9008154
Abstract
摘要

相似文献

1
Mutator specificity and disease: looking over the FENce.突变特异性与疾病:审视FENce
Cell. 1997 Jan 24;88(2):155-8. doi: 10.1016/s0092-8674(00)81832-2.
2
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair.一种依赖酿酒酵母RAD27的新型突变避免机制不同于DNA错配修复。
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3
Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage.鉴定在避免突变、重复序列不稳定和瓣状结构切割方面具有不同缺陷的rad27突变。
Mol Cell Biol. 2001 Aug;21(15):4889-99. doi: 10.1128/MCB.21.15.4889-4899.2001.
4
Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage.Slx4在DNA损伤后以Mec1/Tel1依赖的方式发生磷酸化,并且是DNA烷基化损伤修复所必需的。
Biochem J. 2005 Oct 15;391(Pt 2):325-33. doi: 10.1042/BJ20050768.
5
Subnuclear Relocalization of Structure-Specific Endonucleases in Response to DNA Damage.结构特异性核酸内切酶在 DNA 损伤响应中的亚核重定位。
Cell Rep. 2017 Aug 15;20(7):1553-1562. doi: 10.1016/j.celrep.2017.07.059.
6
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants.酿酒酵母复制和重组缺陷突变体中的染色体大片段重排
Nat Genet. 1999 Sep;23(1):81-5. doi: 10.1038/12687.
7
A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events.FEN-1在非同源DNA末端连接中的作用:链退火和核酸酶处理事件的顺序
Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1303-8. doi: 10.1073/pnas.96.4.1303.
8
The role of SOS and flap processing in microsatellite instability in Escherichia coli.SOS及侧翼加工在大肠杆菌微卫星不稳定性中的作用
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10003-8. doi: 10.1073/pnas.95.17.10003.
9
Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins.DNA损伤反应的编排:检查点蛋白与修复蛋白之间的时空关系
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10
Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells.Rad2/XPG 家族核酸内切酶过表达对酵母和人类细胞基因组完整性的差异影响。
DNA Repair (Amst). 2017 Sep;57:66-75. doi: 10.1016/j.dnarep.2017.06.030. Epub 2017 Jul 3.

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Mol Cell Biol. 1999 Aug;19(8):5675-84. doi: 10.1128/MCB.19.8.5675.
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Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.携带RAD27缺失的酵母突变菌株中单链DNA的积累和端粒重复序列的不稳定。
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Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.MSH2基因发生突变的酵母杂合菌株的突变体表型。
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Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability.DNA错配修复缺陷宿主的肿瘤在基因组不稳定性方面表现出显著增加。
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8739-43. doi: 10.1073/pnas.95.15.8739.
10
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).通过影响参与冈崎片段加工的核酸酶(rad27)和DNA聚合酶δ(pol3-t)的突变来破坏酵母微卫星和小卫星DNA序列的稳定性。
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